Fig. 5
From: The role of cell lysis and matrix deposition in tumor growth modeling
Effect of presence, deposition and absence of ECM. Volume fraction of TCs (a), IFP (b), mass fraction of oxygen (c) and volume fraction of necrotic cells (d) at different times along the radius of the spheroid. In the Figures dashed lines refer to the case of the MTS growing in an ECM scaffold, solid lines refer to the case of the MTS growing in an ECM deposited by TCs and dotted line refers to the case of the MTS growing in an ECM-free culture medium.